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Ending balance Stockholders' Equity Attributable to Parent Stockholders' Equity Stockholders' equity: Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity [Abstract] Stockholders' Equity Note [Abstract] Subsequent Event [Member] Subsequent Event Type [Domain] Subsequent Event Type [Axis] Series C 6% super dividend redeemable convertible preferred stock liquidation value Series C 6% super dividend redeemable convertible preferred stock, shares authorized (in shares) Series C 6% super dividend redeemable convertible preferred stock; 1,000 shares authorized, 176 issued and outstanding at December 31, 2021 and 2020, redemption value: $8,441,000, liquidation value: $1,786,000 at December 31, 2021 Beginning balance Ending balance Series C 6% super dividend redeemable convertible preferred stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Series C 6% super dividend redeemable convertible preferred stock, shares issued (in shares) Series C 6% super dividend redeemable convertible preferred stock, redemption value Convertible preferred stock, redemption value Financial Instruments [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Use of Estimates Use of Estimates, Policy [Policy Text Block] Key Assumptions [Abstract] Warrants [Member] Fair value of warrants Warrants and Rights Outstanding Warrants and rights outstanding, measurement input Outstanding Warrants [Abstract] Warrants and Rights Note Disclosure [Abstract] Weighted average common and potential common shares outstanding - diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Weighted average common and potential common shares outstanding - basic (in shares) Weighted Average Number of Shares Outstanding, Basic Richard E. Uihlein [Member] Counterparty Name [Axis] Chief Executive Officer [Member] Mr. Uihlein [Member] Director [Member] Maximum [Member] Minimum [Member] Ownership [Domain] Ownership [Axis] Statistical Measurement [Domain] Statistical Measurement [Axis] Counterparty Name [Domain] Forecast [Member] Scenario [Domain] Scenario [Axis] Title of Individual [Domain] Title of Individual [Axis] Cover [Abstract] Document Type Document Annual Report Document Transition Report Entity Interactive Data Current Amendment Flag ICFR Auditor Attestation Flag Document Fiscal Year Focus Document Fiscal Period Focus Document Period End Date Entity Registrant Name Entity Central Index Key Entity File Number Entity Tax Identification Number Entity Incorporation, State or Country Code Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Shell Company Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Public Float Entity Address, Address Line One Entity Address, Address Line Two Entity Address, Address Line Three Entity Address, City or Town Entity Address, State or Province Entity Address, Country Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Common Stock, Shares Outstanding Auditor Name Auditor Location Auditor Firm ID Long lived, depreciable assets in the form of computer and office equipment. Computer and Office Equipment [Member] Computer and Office Equipment [Member] Nature of Business, Basis of Presentations and Liquidity [Abstract] Nature of Business, Basis of Presentation and Liquidity [Abstract] The currently estimated costs of trial and general overhead. Accrual to Cover Estimated Cost of Trial Additional estimated costs of clinical trial and general overhead Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development costs and other. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Research and Development Costs and Other Current Accrued research and development costs and other Disclosure of accounting policy for prepaid expenses and other current assets. Prepaid Expenses and Other Current Assets [Policy Text Block] Prepaid Expenses and Other Current Assets Disclosure of accounting policy for security deposit. Security Deposit [Policy Text Block] Security Deposit Disclosure of accounting policy for accrued expense. Accrued Expense [Policy Text Block] Accrued Expenses Name of counterparty. A counterparty is the other party that participates in a financial transaction. SBH Sciences, Inc. [Member] SBH [Member] Capital contribution expense. Capital Contribution Expense Contribution for expenses Name of entity. Galectin Sciences, LLC [Member] Galectin Sciences, LLC [Member] Amount of paid and unpaid temporary equity dividends declared with the form of settlement in cash. Temporary Equity Dividends Series C super dividend redeemable convertible preferred stock dividend Amount of paid and unpaid convertible preferred stock dividends declared with the form of settlement in cash. Convertible Preferred Stock, Dividends Series A 12% convertible preferred stock dividend Number of shares of Convertible preferred stock issued as dividends during the period. Excludes stock splits. Convertible Preferred Stock Dividends, Shares Series A 12% convertible preferred stock dividend (in shares) Number of shares of common stock issued as dividends for temporary equity during the period. Temporary Equity Dividends, Shares Series C super dividend redeemable convertible preferred stock dividend (in shares) Equity impact of the value of stock issued from the exercise of warrants. Stock Issued During Period Value Warrant Exercise Issuance of common stock for warrant exercises Number of new stock issued upon the exercise of warrants during the period. Stock Issued During Period Shares Warrant Exercise Issuance of common stock for warrant exercises (in shares) Warrants [Abstract] Warrants [Abstract] The entire disclosure for Equity warrants are instruments that bestow upon the holder of the instrument the right to buy a particular stock at a predetermined price within a stipulated time frame. ... This payment is to be adjusted against the final payment that needs to be paid in case the warrants are exercised. Common Stock Warrants Disclosure [Text Block] Warrants The federal and state research and development credits expiration year. Federal and State Research and Development Credits Expiration Year Federal and state research and development credits expiration year The deferred tax assets valuation allowance percentage in each of the last two years. Deferred Tax Assets Valuation Allowance Percentage Deferred tax asset valuation allowance percentage in each of the last two years Expiration year of each operating loss carryforward included in operating loss carryforward, in YYYY format. Operating Loss Carryforwards Expiration Year Operating loss carryforwards expiration year Number of consecutive trading days, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Includes, but not limited to, weeks in a year or quarter. Number of Consecutive Trading Days Number of consecutive trading days Shares of Series C were converted into common stock and post conversion dividend rights were issued. Post Conversion Dividend Rights Issued Post conversion dividend rights (in shares) Common stock issued per each converted share of Series C (accrued and unpaid dividends will be issued as additional shares). Common Shares Issuable Upon Conversion of Convertible Stock Common stock shares issued (in shares) Net sales until the total dividends paid is equal to the initial investment as percentage of total net sales. Dividend as Percentage of Net Sales Dividend as percentage of net sales Number of days for preferred stock post conversion rights in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Includes, but not limited to, weeks in a year or quarter. Closing Days After Conversion Rights Closing days after conversion rights Number of warrants or rights issued during the period. Class of Warrant or Right Issued Warrants issued (in shares) Number issued (in shares) Multiplied by the preferred stock post conversion redemption right shall be equal the applicable return on investment ("ROI") percentage. Post Conversion Redemption Right Return on Investment Multiplier Amount Post conversion redemption right, return on investment multiplier amount Proceeds from issuance of capital stock which provides for a specific dividend that is paid to the shareholders before any dividends to common stockholders and which takes precedence over common stockholders in the event of liquidation. Proceeds from Issuance of Preferred Stock, Net of Issuance Costs Net proceeds from issuance of preferred stock Amount per share or per unit assigned to the consideration received of equity securities issued for development stage entities. Equity Issuance Per Share Amount Common stock share conversion price (in dollars per share) Dividend payment scenario. Dividend Payment Scenario Two [Member] Dividend Payment Scenario Two [Member] Scenario 2 [Member] Dividend payment scenario. Dividend Payment Scenario One [Member] Dividend Payment Scenario One [Member] Scenario 1 [Member] Issuance price per share or per unit of warrants or rights outstanding. Warrants Issued Price Warrants issued price (in dollars per share) Date the warrants or rights are expired, in YYYY-MM-DD format. Class Of Warrant Or Rights Date From Which Warrants Or Rights Expired Expiration date Date the warrants or rights are issued, in YYYY-MM-DD format. Warrant Issue Date Warrant issue date Name of the class or type of warrants. May Twenty Three Twenty Ninteen Rights Offering Warrants [Member] May 23, 2019 Rights offering warrants [Member] Name of the class or type of warrants. September Twenty Nine Twenty Sixteen Series B Three Transaction [Member] September 29, 2016 Series B-3 Transaction [Member] Name of the class or type of warrants. November Four Twenty Zero Nine Series B Two Transaction [Member] November 4, 2009 Series B-2 Transaction [Member] Name of the class or type of warrants. December Twenty Three Twenty Sixteen Series B Three Transaction [Member] December 23, 2016 Series B-3 Transaction [Member] Name of the class or type of warrants. February Twelve Two Thousand Zero Nine Series B One Transaction Member February 12, 2009 Series B-1 Transaction [Member] Name of the class or type of warrants. August Twelve Twenty Zero Nine Series B Two Transaction [Member] August 12, 2009 Series B-2 Transaction [Member] Name of the class or type of warrants. May Thirteen Twenty Zero Nine Series B Two Transaction [Member] May 13, 2009 Series B-2 Transaction [Member] Name of the class or type of warrants. September Thirty Twenty Zero Nine Series B Two Transaction [Member] September 30, 2009 Series B-2 Transaction [Member] Name of the class or type of warrants. December Twenty Eight Twenty Sixteen Private Placement [Member] December 28, 2016 Private Placement Warrants [Member] Name of the class or type of warrants. September Twenty Two Twenty Sixteen Series B Three Transaction [Member] September 22, 2016 Series B-3 Transaction [Member] Name of the class or type of warrants. May Ten Twenty Ten Series B Two Transaction [Member] May 10, 2010 Series B-2 Transaction [Member] Name of the class or type of warrants. June Thirty Twenty Zero Nine Series B Two Transaction [Member] June 30, 2009 Series B-2 Transaction [Member] Name of the class or type of warrants. December Eight Twenty Zero Nine Series B Two Transaction [Member] December 8, 2009 Series B-2 Transaction [Member] Name of the class or type of warrants. April Thirty Twenty Ten Series B Two Transaction [Member] April 30, 2010 Series B-2 Transaction [Member] Name of the class or type of warrants. March Eight Twenty Ten Series B Two Transaction [Member] March 8, 2010 Series B-2 Transaction [Member] Name of the class or type of warrants. February Twenty Seven Twenty Seventeen Private Placement [Member] February 27, 2017 Private Placement Warrants [Member] Name of the class or type of warrants. January Twenty Nine Twenty Ten Series B Two Transaction [Member] January 29, 2010 Series B-2 Transaction [Member] Name of the class or type of warrants. Twenty Eighteen And Twenty Seventeen Warrants Issued For Services [Member] 2018 and 2017 Warrants issued for services [Member] Name of the class or type of warrants. December Twenty Two Twenty Sixteen Private Placement [Member] December 22, 2016 Private Placement Warrants [Member] Share based Compensation Arrangement by Share based Payment Award Equity Instruments Other Than Options Weighted Average Exercise Price [Abstract] Weighted Average Exercise Price [Abstract] Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan. Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Outstanding Weighted Average Exercise Price Outstanding at end of period (in dollars per share) Outstanding at beginning of period (in dollars per share) Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated. Share based Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Forfeitures In Period Weighted Average Exercise Price Forfeited/cancelled (in dollars per share) Weighted average price at which option holders acquired shares when converting their stock options into shares. Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Exercises In Period Weighted Average Exercise Price Exercised (in dollars per share) Amount reclassified from accrued compensation to excess of issue price over par or stated value of stock and from other transaction involving stock or stockholder. Includes, but is not limited to, additional paid-in capital (APIC) for common and preferred stock. Reclassification Of Accrued Bonus To Additional Paid In Capital Reclassification of accrued bonus to additional paid in capital The fair value of the contingent interest derivative liability related to related party convertible note payable. Fair Value Of Derivative Related To Related Party Convertible Note Payable Fair value of derivatives regarding related party convertible notes payable Amount of aggregate offering price of common stock which can be sold from time to time through the sales agent. Aggregate Offering Price Aggregate offering price Agreement with a sales agent under which the Company may issue and sell shares of its common stock. Two Thousand Seventeen Market Agreement [Member] 2017 Market Agreement [Member] Agreement with a sales agent under which the Company may issue and sell shares of its common stock. Two Thousand Twenty Market Agreement [Member] 2020 Market Agreement [Member] The maximum number of undesignated capital stock permitted to be issued by an entity's charter and bylaws. Undesignated Capital Stock, Shares Authorized Undesignated stock, shares authorized (in shares) Series B-3 Preferred stock that may be exchanged into common shares or other types of securities at the owner's option. Each share of the Series B-3 is entitled to dividends at the rate of 8% per annum. Series B Three Convertible Preferred Stock [Member] Series B-3 Convertible Preferred Stock [Member] Series B-2 Preferred stock that may be exchanged into common shares or other types of securities at the owner's option. Each share of the Series B-2 is entitled to dividends at the rate of 12% per annum. Series B Two Convertible Preferred Stock [Member] Series B-2 Convertible Preferred Stock [Member] Percentage of commission rate to be paid to sales agent in gross proceeds from the sale of common stock. Commission Rate Percentage of commission rate to be paid to sales agent Series B-1 Preferred stock that may be exchanged into common shares or other types of securities at the owner's option. Each share of the Series B-1 is entitled to dividends at the rate of 12% per annum. Series B One Convertible Preferred Stock [Member] Series B-1 Convertible Preferred Stock [Member] Return on Investments Percentage [Abstract] ROI Percentage [Abstract] Return on investments after seventh anniversary but before eighth anniversary of date of issuance. Return on Investments Percentage, Period Seven ROI after seventh anniversary but before eighth anniversary of date of issuance Return on investments percentage before second anniversary of date of issuance. Return on Investments Percentage, Period One ROI before second anniversary of date of issuance Return on investments after fourth anniversary but before fifth anniversary of date of issuance. Return on Investments Percentage, Period Four ROI after fourth anniversary but before fifth anniversary of date of issuance Return on investments after fifth anniversary but before sixth anniversary of date of issuance. Return on Investments Percentage, Period Five ROI after fifth anniversary but before sixth anniversary of date of issuance Return on investments after second anniversary but before third anniversary of date of issuance. Return on Investments Percentage, Period Two ROI after second anniversary but before third anniversary of date of issuance Number of voting rights of convertible preferred stock. Includes eligibility to vote and votes per share owned. Convertible Preferred Stock, Number of Voting Rights Convertible preferred stock, voting rights Return on investments after sixth anniversary but before seventh anniversary of date of issuance. Return on Investments Percentage, Period Six ROI after sixth anniversary but before seventh anniversary of date of issuance Return on investments after eighth anniversary but before ninth anniversary of date of issuance. Return on Investments Percentage, Period Eight ROI after eighth anniversary but before ninth anniversary of date of issuance Return on investments after third anniversary but before fourth anniversary of date of issuance. Return on Investments Percentage, Period Three ROI after third anniversary but before fourth anniversary of date of issuance Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Aggregate Intrinsic Value [Abstract] Share Based Compensation Arrangement By Share Based Payment Award Options Weighted Average Remaining Term [Abstract] Weighted Average Remaining Contractual Life [Abstract] Aggregate par or stated value of shares which are not designated as common stock or preferred stock. Undesignated Capital Stock Value Undesignated stock, $0.01 par value; 20,000,000 shares authorized at December 31, 2021 and 2020, 20,000,000 shares designated at December 31, 2021 and 2020, respectively Carrying value as of the balance sheet date of long-term debt (with maturities initially due after one year or beyond the operating cycle if longer) identified as convertible notes payable and accrued interest, net of debt discount of related party excluding current portion. Convertible Notes Payable is a written promise to pay a note which can be exchanged for a specified amount of another, related security, at the option of the issuer and the holder. Convertible Note Payable and Accrued Interest Net of Debt Discount - Related Party Non-Current Convertible notes payable and accrued interest, net of debt discounts - related party (Note 5) Number of shares of undesignated capital stock which are designated as common stock or preferred stock by board of directors. Undesignated Capital Stock Shares Designated Undesignated stock, shares designated (in shares) Face amount or stated value per share of undesignated capital stock. Undesignated Capital Stock Par Value Undesignated stock, par value (in dollars per share) Equity Incentive Plan Agreement ("Agreement") is a legal contract between a Corporation and its employees to provide the employee with an interest in the Corporation. The purpose of an Equity Incentive Plan is to strengthen the financials of the Corporation by providing incentive stock options to its employees. Incentive Compensation Plan Two thousand Nine Member [Member] Incentive Compensation Plan 2009 [Member] A share-based compensation plan under which awards may be granted for officers, employees and directors of the Company and its subsidiaries. Equity Incentive Plan 2019 [Member] Information about non qualified options Plans. Non Qualified Options Plans [Member] Refers to the terms of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Includes, but not limited to, weeks in a year or quarter. Share-based Compensation Arrangement by Share-based Payment Award, Term of Award Award term Its represented to exercise price range four. Exercise Price Range Four [Member] $5.01 - $8.00 [Member] Its represented to exercise price range two. Exercise Price Range Two [Member] $1.01-$3.00 [Member] Its represented to exercise price range one. Exercise Price Range One [Member] $0.87-$1.00 [Member] Its represented to exercise price range five. Exercise Price Range Five [Member] $8.01-$13.38 [Member] Its represented to exercise price range three. Exercise Price Range Three [Member] $3.01-$5.00 [Member] Options Outstanding [Abstract] Options Exercisable [Abstract] A contractual arrangement with a lender under which borrowings can be made up to a specific amount at any point in time, and under which borrowings outstanding may be either short-term or long-term, depending upon the particulars. Unsecured Line of Credit [Member] Unsecured Line of Credit [Member] Line of Credit, Related Party [Abstract] Line of Credit - Related Party [Abstract] The amount of issuance of warrants. Issuance of Warrants Value Warrants issuance value Clinical Trial and Research Contingencies [Abstract] Free rent period, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Free Rent Period Free rent period Contract cancelation notice period, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Contract Cancelation Notice Period Contract cancelation notice period Number of operating leases during period. Number of Operating Leases Number of operating leases Number of directors of the company. Number of Directors Restricted Stock Grants [Abstract] Percentage of underlying the outstanding whole number of DSUs credited individuals during period. Deferred Compensation Arrangement Percentage of Deferred Share Units Shall be Issued Period Two Percentage of DSUs shall be credited on September 1, 2021 Percentage of underlying the outstanding whole number of DSUs credited individuals during period. Deferred Compensation Arrangement Percentage of Deferred Share Units Shall be Issued Period Three Percentage of DSUs shall be credited on March 1, 2024 The deferred compensation arrangement with individual cash award granted paid in cash percentage. Deferred Compensation Arrangement With Individual Cash Award Granted Paid in Cash Percent Percentage of base salary paid in cash Percentage of underlying the outstanding whole number of DSUs credited individuals during period. Deferred Compensation Arrangement, Percentage of Deferred Share Units Shall be Issued, Period One Percentage of DSUs shall be credited on March 1, 2021 The deferred compensation arrangement with individual cash award granted paid in deferred stock units percentage. Deferred Compensation Arrangement With Individual Cash Award Granted Paid in Deferred Stock Units Percent Percentage of base salary paid in deferred stock units Bonus shares are additional shares given to the existing shareholders. Bonus Shares [Member] Bonus Shares [Member] Shares relating to prior conversion dividend rights. Shares Relating to Prorated Dividend Prior to Conversion Shares relating to prorated dividend prior to conversion (in shares) Percentage of weighted average stock price for dividends prior to payment date. Percentage of Weighted Average Stock Price for Dividends Prior to Payment Date Weighted average price percentage The derivative liability of contingent interest September Note. Contingent Interest, September Note [Member] September Note [Member] The derivative liability of contingent interest April Note. Contingent Interest, April Note [Member] April Note [Member] The derivative liability of contingent interest December Note. Contingent Interest, December Note [Member] December Note [Member] Convertible Notes Payable, Related Party [Abstract] Convertible Notes Payable - Related Party [Abstract] The number of promissory notes executed under the loans agreement. Number of Promissory Notes Executed Number of promissory notes executed Contingent interest rate per annum for funds borrowed, under the debt agreement. Annual Interest Rate Additional interest rate per annum from issuance date to maturity date period The number of promissory notes evidenced by loans agreement. Number of Promissory Notes Evidenced by Loans Agreement Number of promissory notes evidenced by loans agreement The number of loans closing under the loans agreement. Number of Loans Closing Number of loans closing Contingent interest rate per quarter for funds borrowed, under the debt agreement. Quarterly Interest Rate Additional interest rate per quarter The type of debt instrument. April Convertible Promissory Note [Member] April Note [Member] The type of debt instrument. December Convertible Promissory Note [Member] December Note [Member] A type of debt instrument. September Convertible Promissory Note [Member] September Note [Member] A type of debt instrument. Second Closing [Member] A type of debt instrument. First Closing [Member]